RGS17 antibody

Catalog No. ABIN7118379

This anti-RGS17 antibody is a Rabbit Polyclonal antibody detecting RGS17 in WB, ELISA, IF and IHC. Suitable for Human and Mouse.

Quick Overview for RGS17 antibody (ABIN7118379)

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-RGS17 Antibody

Purpose: RGS17 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: regulator of G-protein signaling 17

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RGS17

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Alternative Name: RGS17

Background:

Synonyms: Regulator of G-protein signaling 17 (RGS17)|RGS17|RGSZ2

Background: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins(By similarity).

Molecular Weight: 27 kDa

Gene ID: 26575

UniProt: Q9UGC6

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling